"Handy Andy" is a humorous and satirical tale of Irish life, featuring a likable but unlucky protagonist named Andy Rooney, known for his "handiness" or skill in various trades. The novel follows Andy as he tries to make a living and win the heart of his love interest, Biddy O'Brien, despite his many misadventures. Along the way, the novel vividly portrays Irish society and culture, including its traditions, language, and music.